Brett Froeliger
Brett Froeliger
My program of research has been continuously funded by NIH since 2012. I have
published over 60 peer reviewed manuscripts, book chapters and reviews articles and am an Associate Editor for Nicotine & Tobacco Research, Frontiers in Psychiatry and Evidence-Based Complementary and Alternative Medicine. In addition to conducting research, I'm dedicated to educating the next generation of addiction scientists.
- Ph.D. in Psychology, Southern Illinois University- Carbondale
- M.A. in Psychology, Southern Illinois University- Carbondale
- B.A. in Psychology, Southern Illinois University- Carbondale
Halbert CH, Jefferson MS, Danielson C, Froeliger, B, Giordanoa A, Thaxton J. (in press). An observational study and randomized trial of stress reactivity in cancer disparities. Health Psychology.
McConnell, P. A., E. L. Garland, J. K. Zubieta, R. Newman-Norlund, S. Powers and Froeliger, B. (2020). "Impaired frontostriatal functional connectivity among chronic opioid using pain patients is associated with dysregulated affect." Addict Biol. PMID: 30945801
Newman-Norlund, R., Gibson, M., McConnell, P., Froeliger, B. (2020). Dissociable effects of theta-burst repeated transcranial magnetic stimulation to the inferior frontal gyrus on inhibitory control in nicotine addiction. Frontiers in Psychiatry. Apr 15;11:260. PMID: 32351412
Garland, E.L., Atchley, R., Howard, M., Zubieta, J-K., Froeliger, B. (2019). Mindfulness-Oriented Recovery Enhancement Restructures Reward Processing Among Chronic Opioid Users: Neurophysiological and Affective Evidence. Science Advances 5(10). PMID 31663023
Tomko, R. L., Froeliger, B., McClure, E. A., Saladin, M.E., and Gray, K.M. (2019). Gender Differences in Smoking Latency Following Exposure to Stressful Images Administered in Naturalistic Settings. Journal of Womens Health. 28 (11): 1593-1593.
Fridriksson, J.F., Rorden, C., Newman-Norlund, R., Froeliger, B., Thrasher, J. (2018). Smokers' Neurological Responses to Novel and Repeated Health Warning Labels (HWLs) from Cigarette Packages. Frontiers in Psychology.
Garland EL, Bryan CJ, Kreighbaum L, Nakamura Y, Howard MO & Froeliger B. (2018). Prescription opioid misusing chronic pain patients exhibit dysregulated context-dependent associations: Investigating associative learning in addiction with the Cue-Primed Reactivity Task. Drug and Alcohol Dependence. Mar 27;187:13-21.PMID: 29626741
Garland, E.L., Hanley, A.W., Bedford, C., Zubieta, J.-K., Howard, M.O., Nakamura, Y., Donaldson, G., & Froeliger, B. (2018). Reappraisal deficits promote craving and emotional distress among chronic pain patients at risk for prescription opioid misuse. Journal of Addictive Diseases. Jun 4:1-9. PMID: 29863439.
Serfaty, S., Gale, G., Beadman, M., Froeliger, B., & Kamboj, S. K. (2018). Mindfulness, Acceptance and Defusion Strategies in Smokers: a Systematic Review of Laboratory Studies. Mindfulness (N Y), 9(1), 44-58. doi:10.1007/s12671-017-0767-1
Badran, B.W., Austelle, C.W., Smith, N.R., Glusman, C.E., Froeliger, B., Garland, E.L., Borckardt, J.J., George, M.S., Short, B. (2017). A double-blind study exploring the use of transcranial direct current stimulation (tic’s) to potentially enhance mindfulness meditation (E-meditation). Brain Stimulation. Jan-Feb; 10 (1): 152-154. PMID: 27839723.
Carpenter MJ, Heckman BW, Wahlquist AE, Wagener TL, Goniewicz ML, Gray KM, Froeliger B, Cummings KM. A naturalistic, randomized pilot trial of e-cigarettes: Uptake, exposure, and behavioral effects. Cancer Epidemiology, Biomarkers & Prevention. 2017;26:1795-803. PMCID: 5713898.
Froeliger, B., Mathew, A.R., McConnell, P.A., Eichberg, C., Saladin, M.E., Carpenter, M.J., Garland, E.L. (2017). Restructuring Reward Mechanisms in Nicotine Addiction: A Pilot fMRI Study of Mindfulness-Oriented Recovery Enhancement for Cigarette Smokers. Evidence-Based Complementary and Alternative Medicine: eCAM 2017.
Froeliger, B., McConnell, P.A., Sweitzer, M.A., Bell, S., Kozink, R.V., Eichberg, C., Gray, K.M., McClernon, F.J. (2017). Association Between Baseline Corticothalamic-Mediated Inhibitory Control and Smoking Relapse Vulnerability. JAMA Psychiatry. Mar 1. doi:10.1001/jamapsychiatry.2017.0017
Garland, E.L., Howard, M.O.. Zubieta, J.K., Froeliger, B. (2017). Restructuring Hedonic Dysregulation in Chronic Pain and Prescription Opioid Misuse: Effects of Mindfulness-Oriented Recovery Enhancement on Responsiveness to Drug Cues and Natural Rewards. Psychotherapy and Psychosomatics. Feb 10;86(2):111-112. PMID: 28183077
Germeroth, L.J., Carpenter, M.J., Baker, N.L., Froeliger, B., LaRowe, S.D., Saladin, M.E. (2017). A Brief Memory Updating Intervention Significantly Attenuates Smoking Behavior. JAMA Psychiatry. Feb 1.PMID: 28146243.
Meier, E., Wahlquist, A.E., Heckman, B.W., Cummings, K.M., Froeliger, B., Carpenter, M.J. (2017). A Pilot Randomized Crossover Trial of E-cigarette Sampling Among Smokers. Nicotine and Tobacco Research, Feb; 19 (2): 176-182. PMID: 27613880.
Addicott, M.A., Sweitzer, M.M., Froeliger, B., McClernon, F.J. (2015). Increased functional connectivity in an insula-based network is associated with improved smoking cessation outcomes. Neuropsychopharmacology; Oct; 40 (11): 2648-56. PMID: 25895453.
Froeliger, B., McConnell, P.A., Stankeviciute, N., McClure, E.A., Kalivas, P.W., Gray, K.M. (2015). The effects of N-Acetylcysteine on frontostriatal resting-state functional connectivity, withdrawal symptoms and smoking abstinence: A double-blind, placebo-controlled fMRI pilot study. Drug and Alcohol Dependence. doi:10.1016/j.drugalcdep.2015.09.021. PMID: 26454838.
Garland, E.L., Froeliger, B., Howard, M.O. (2015). Neurophysiological Evidence for Remediation of Reward Processing Deficits in Chronic Pain and Opioid Misuse Following Treatment with Mindfulness-Oriented Recovery Enhancement: Exploratory ERP Findings from a Pilot RCT. Journal of Behavioral Medicine. Jun;82(3):448-59. doi: 10.1007/s10865-014-9607-0. Epub 2014 Nov 11. PMID: 25385024.
Garland, E, Hanley, A., Farb, N., Froeliger, B. (2015). State Mindfulness During Meditation Predicts Enhanced Cognitive Reappraisal. Mindfulness. Apr 1;6(2):234-242. PMID: 26085851.
Heckman, B., Carpenter, M., Correa, J., Wray, J., Saladin, M., Froeliger, B., Drobes, D., Brandon, T. (2015). Acute Negative Affect Manipulations Increase Smoking Behavior: A Meta-Analysis. Addiction. May;110(5):751-60. PMID: 25641624.
McClure, E.A., Baker, N.L., Gipson, C.D., Carpenter, M.J., Roper, A., Froeliger, B.E, Kalivas, P.W., Gray, K.M (2015). An open-label pilot trial of N-acetylcysteine and varenicline in adult cigarette smokers. The American Journal of Drug and Alcohol Abuse. Jan;41(1):52-6. PMID: 25062287.
McConnell, P.A., Froeliger, B. (2015). Mindfulness, Mechanisms and Meaning: Perspectives from the Cognitive Neuroscience of Addiction. Psychological Inquiry. PMID: 26924915.
Addicott, M.A., Froeliger, B., Kozink, R.V., Van Wert, D.M., Westman, E.C., Rose, J.E., McClernon, F.J. (2014). Nicotine and non-nicotine smoking factors differentially modulate craving, withdrawal and cerebral blood flow as measured with arterial spin labeling. Neuropsychopharmacology. Nov;39(12):2750-9. PMID: 24820539.
Garland, E.L., Manusov, E., Froeliger, B., Kelly, A., Williams, J., Howard, M. (2014). Mindfulness-Oriented Recovery Enhancement for Chronic Pain and Prescription Opioid Misuse: Results from an Early Stage Randomized Controlled Trial. Journal of Consulting and Clinical Psychology. Jun;82(3):448-59. PMID: 24491075.
Newman-Norlund, R., Thrasher, J., Fridrikson, J., Brixius, W., Froeliger, B., Hammond, D., Cummings, M. (2014). Neural biomarkers for assessing the effects of different types of imagery in pictorial health warning labels on cigarette packaging. BMJ Open. Dec 31;4(12). PMID: 25552613.
Froeliger, B., Modlin, L.A., Kozink, R.V., Wang, L., Garland, E.L., Addicott, M.A., McClernon, F.J. (2013). Frontoparietal Attentional Network Activation Differs Between Smokers and Nonsmokers During Affective Cognition. Psychiatry Research: Neuroimaging. Jan 30;211(1):57-63. PMID: 23154092.
Garland, E. L., Froeliger, B., Zeidan, F., Suveg, K., & Howard, M. O. (2013). The downward spiral of chronic pain, prescription opioid misuse, and addiction: Cognitive, affective, and neuropsychopharmacologic pathways. Neuroscience & Biobehavioral Reviews. Dec;37(10 Pt 2):2597-607. PMID: 23988582.Froeliger, B. Garland, E., & McClernon, F.J. (2012). Yoga meditation practitioners exhibit greater gray matter volume and fewer reported cognitive failures: Results of a preliminary voxel-based morphometric analysis. Evidence-Based Complementary and Alternative Medicine: eCAM 2012: 821307. PMID: 23304217.
Froeliger, B., Beckham, J.C., Feldman, M., Kozink, R.V., McClernon, F.J. (2012). Effects of nicotine administration on emotional reactivity in PTSD and non-PTSD smokers: Results of a preliminary fMRI study. Advances in Pharmacological Sciences, vol 2012, Article ID 265724, 6 pages. PMID: 22719754.
Froeliger, B., Garland, E.L., Modlin, L.A., McClernon, F.J. (2012). Neurocognitive correlates of the effects of yoga meditation practice on emotion and cognition: a pilot study. Frontiers in Integrative Neuroscience, 6. PMID: 22855674
Froeliger, B., Garland, E.L., Kozink, R.V. et al., (2012) Meditation-State Functional Connectivity (msFC): Strengthening of the Dorsal Attention Network and Beyond, Evidence-Based Complementary and Alternative Medicine. vol. 2012, Article ID 680407, 9 pages, 2012. PMID: 22536289.
Froeliger, B., Modlin, L.A., Kozink, R.V., Wang, L., McClernon, F.J. (2012). Smoking Abstinence and Depressive Symptoms Modulates the Executive Control System During Emotional Information Processing. Addiction Biology,17, 668-679. PMID: 22081878.
Froeliger, B., Modlin, L.A., Wang, L., Kozink, R.V., McClernon, F.J. (2012). Nicotine Withdrawal Modulates Frontal Brain Function During an Affective Stroop Task. Psychopharmacology, 220, 707-18. PMID: 21989805.
Rose, J.E., McClernon, F.J., Froeliger, B., Behm, F.M., Preud'homme, X., Krystal, A. (2011). Repetitive transcranial magnetic stimulation (rTMS) of the superior frontal gyrus modulates craving for cigarettes. Biological Psychiatry, 70, 794-799. PMID: 21762878.
Froeliger, B., Kozink, R.V., Rose, J.E., Behm, F.M., Salley, A.N., and McClernon, F.J. (2010). Hippocampal and striatal grey matter volume are associated with a smoking cessation treatment outcome: Results of an exploratory voxel-based morphometric analysis. Psychopharmacology, 210, 577-583. PMID: 20424827.
Kozink, R. V., Lutz, A. M., Rose, J. E., Froeliger, B., & McClernon, F. J. (2010). Smoking withdrawal shifts the spatiotemporal dynamics of neurocognition. Addiction Biology, 15, 480-490. PMID: 21040240.
Froeliger, B., Gilbert, D.G., & McClernon, F.J. (2009). Effects of Nicotine on Novelty Detection and Memory Recognition Performance: Double-Blind, Placebo-Controlled Studies of Smokers and Nonsmokers. Psychopharmacology, 205, 625-633. PMID: 19488741.
Gilbert, D. G., Sugai, C., Zuo, Y., Rabinovich, N. E., McClernon, F. J., & Froeliger, B. E. (2007). Brain indices of nicotine’s effects on attentional bias to smoking and emotional pictures and to task-relevant targets. Nicotine and Tobacco Research, 9, 351-363. PMID: 17365767.